

Top Cast

Chris Rock
Osmosis Jones (voice)

Laurence Fishburne
Thrax (voice)

David Hyde Pierce
Drix (voice)

Brandy Norwood
Leah (voice)

Elena Franklin
Shane Detorre

Bill Murray
Frank Detorre

William Shatner
Mayor Phlegmming (voice)

Ron Howard
Tom Colonic (voice)

Kid Rock
Kidney Rock (voice)

Molly Shannon
Mrs. Boyd

Chris Elliott
Bob

Jonathan Adams
Officer Tom (voice)
Key Film Crew
Production Stats
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